Research Output 1985 2018

2018
1 Citation (Scopus)

Possible protective mechanisms exerted by metformin or metformin and vitamin E in isoproterenol-induced cardiac injury

Al-Rasheed, N. M., Al-Rasheed, N. M., AL-Rabeeah, D. A., AL-Barrak, H. S., AL-Salman, S. A., Ibrahim, S. A., AL-Hassab, S. A., Al-Amin, M. A., Hasan, I. H., Al-Ajmi, H. N. & AL-Shammari, T. K., 1 May 2018, In : Journal of Cellular Biochemistry. 119, 5, p. 3903-3912 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Metformin
Vitamin E
Isoproterenol
Wounds and Injuries
Myocardial Infarction

Roles of some antioxidants in modulation of cardiac myopathy induced by sodium nitrite via down-regulation of mRNA expression of NF-κB, Bax, and flt-1 and suppressing DNA damage

Fadda, L. M., Attia, H. A., Al-Rasheed, N. M., Ali, H. M. & Al-Rasheed, N. M., 1 Feb 2018, In : Saudi Pharmaceutical Journal. 26, 2, p. 217-223 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Sodium Nitrite
Muscular Diseases
DNA Damage
Quercetin
Melatonin
1 Citation (Scopus)

Topical simvastatin gel as a novel therapeutic modality for palatal donor site wound healing following free gingival graft procedure

Madi, M. & Kassem, A., 3 Apr 2018, In : Acta Odontologica Scandinavica. 76, 3, p. 212-219 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Simvastatin
Wound Healing
Gels
Tissue Donors
Transplants
3 Citations (Scopus)

Validation of knowledge and adherence assessment tools among patients on warfarin therapy in a Saudi hospital anticoagulant clinic

Shilbayeh, S. A. R., Almutairi, W. A., Alyahya, S. A., Alshammari, N. H., Shaheen, E. & Adam, A., 1 Feb 2018, In : International Journal of Clinical Pharmacy. 40, 1, p. 56-66 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Warfarin
Anticoagulants
International Normalized Ratio
Medication Adherence
Patient Compliance
2017
9 Citations (Scopus)

Adamantane-isothiourea hybrid derivatives: Synthesis, characterization, in vitro antimicrobial, and in vivo hypoglycemic activities

Al-Wahaibi, L. H., Hassan, H. M., Abo-Kamar, A. M., Ghabbour, H. A. & El-Emam, A. A., 1 May 2017, In : Molecules. 22, 5, 710.

Research output: Contribution to journalArticleResearchpeer-review

Adamantane
Hypoglycemic Agents
Bacteria
Nuclear magnetic resonance
Gliclazide
10 Citations (Scopus)

Altered AMPA receptor expression plays an important role in inducing bidirectional synaptic plasticity during contextual fear memory reconsolidation

Bhattacharya, S., Kimble, W., Buabeid, M., Bhattacharya, D., Bloemer, J., Alhowail, A., Reed, M., Dhanasekaran, M., Escobar, M. & Suppiramaniam, V., 1 Mar 2017, In : Neurobiology of Learning and Memory. 139, p. 98-108 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Neuronal Plasticity
AMPA Receptors
Fear
Glutamate Receptors
Endocytosis
3 Citations (Scopus)

Amelioration of panadol-induced nephrotoxicity via down-regulation of Bax/Bcl2 ratio with some antioxidants

Al-Rasheed, N., Faddah, L. M., Hasan, I. H., Ali, H. M., Al-Rasheed, N., El Oraby, N. F. & Mohamed, M. H., 1 Oct 2017, In : Pharmacological Reports. 69, 5, p. 1088-1093 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Acetaminophen
Down-Regulation
Antioxidants
Kidney
Curcumin
2 Citations (Scopus)

Bax and CD68 expression in response to liver injury induced by acetaminophen: The hepatoprotective role of thymoquinone and curcumin

Fadda, L. M., Al-Rasheed, N. M., Hasan, I. H., Ali, H. M., Al-Rasheed, N. M., Al-Fayez, M., Ahmed, A. M., Almutlaq, N., Qasem, N. & Khalaf, R., 1 Jan 2017, In : Pakistan Journal of Zoology. 49, 1, p. 85-93 9 p.

Research output: Contribution to journalArticleResearchpeer-review

acetaminophen
curcumin
liver
acetylcysteine
antidotes
4 Citations (Scopus)

Crystal structure of 4-bromobenzyl (Z)-N′-(adamantan-1-yl)-4-phenylpiperazine-1-carbothioimidate, C28H34BrN3S

Al-Wahaibi, L. H., Hassan, H. M., Abo-Kamar, A. M., Ghabbour, H. A. & El-Emam, A. A., 1 Mar 2017, In : Zeitschrift fur Kristallographie - New Crystal Structures. 232, 2, p. 189-191 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Crystal structure
crystal structure
phenylpiperazine
1 Citation (Scopus)

Date fruits inhibit hepatocyte apoptosis and modulate the expression of hepatocyte growth factor, cytochrome P450 2E1 and heme oxygenase-1 in carbon tetrachloride-induced liver fibrosis

Al-Rasheed, N. M., Attia, H. A., Mohamad, R. A., Al-Rasheed, N. M., Al Fayez, M. & Al-Amin, M. A., 15 Mar 2017, In : Archives of Physiology and Biochemistry. 123, 2, p. 78-92 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Cytochrome P-450 CYP2E1
Heme Oxygenase-1
Hepatocyte Growth Factor
Carbon Tetrachloride
Liver Cirrhosis
2 Citations (Scopus)

Design, Synthesis, and Biological Evaluation of Some Cyclohepta[b]Thiophene and Substituted Pentahydrocycloheptathieno[2,3-d]Pyrimidine Derivatives

Elmongy, E. I., Khedr, M. A., Taleb, N. A., Awad, H. M. & Abbas, S. E. S., 1 Jan 2017, In : Journal of Heterocyclic Chemistry. 54, 2, p. 1084-1093 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Thiophenes
Pyrimidines
Hydrogen bonds
Derivatives
pyrimidine
1 Citation (Scopus)

Hepatoprotective role of α-Lipoic acid and Thymoquinone in Acetaminophen- Induced liver injury: Down-Regulation of COX-2 and flt-1 expression

Al-Rasheed, N. M., Fadda, L., Al-Rasheed, N. M., Hasan, I. H., Ali, H. M., Al-Fayez, M. & Mohamad, R. A., 1 Jan 2017, In : Brazilian Archives of Biology and Technology. 60, e17160703.

Research output: Contribution to journalArticleResearchpeer-review

Thioctic Acid
Cyclooxygenase 2
Acetaminophen
Down-Regulation
Liver
3 Citations (Scopus)

Immunological alteration & toxic molecular inductions leading to cognitive impairment & neurotoxicity in transgenic mouse model of Alzheimer's disease

Ahuja, M., Buabeid, M., Abdel-Rahman, E., Majrashi, M., Parameshwaran, K., Amin, R., Ramesh, S., Thiruchelvan, K., Pondugula, S., Suppiramaniam, V. & Dhanasekaran, M., 15 May 2017, In : Life Sciences. 177, p. 49-59 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Oxidative stress
Poisons
Transgenic Mice
Brain
Alzheimer Disease
2 Citations (Scopus)

Mechanistic understanding of the effect of renal impairment on metformin oral absorption using computer simulations

Almukainzi, M., Gabr, R., Abdelhamid, G. & Löbenberg, R., 1 Mar 2017, In : Journal of Pharmaceutical Investigation. 47, 2, p. 151-161 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Computer Simulation
Kidney
Renal Insufficiency
Creatinine
Down-Regulation

Protective potential of grape seed proanthocyandins extract against glivec (Imatinib mesylate) induced liver toxicity and oxidative stress in male rats

Al-Rasheed, N. M., El-Masry, T. A., Tousson, E., Hassan, H. M. & Al-Ghadeer, A., 13 Dec 2017, In : Annual Research and Review in Biology. 20, 6, ARRB.37766.

Research output: Contribution to journalArticleResearchpeer-review

Grape Seed Extract
grape seed extract
Oxidative stress
hepatotoxicity
Liver
5 Citations (Scopus)

Pulmonary prophylactic impact of melatonin and/or quercetin: A novel therapy for inflammatory hypoxic stress in rats

Al-Rasheed, N. M., Fadda, L., Attia, H. A., Sharaf, I. A., Mohamed, A. M. & Al-Rasheed, N. M., 1 Mar 2017, In : Acta Pharmaceutica. 67, 1, p. 125-135 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Quercetin
Melatonin
Lung
Heat-Shock Proteins
Sodium Nitrite
2 Citations (Scopus)

Quercetin inhibits sodium nitrite-induced inflammation and apoptosis in different rats organs by suppressing Bax, HIF1-α, TGF-β, Smad-2, and AKT pathways

Al-Rasheed, N. M., Fadda, L. M., Attia, H. A., Ali, H. M. & Al-Rasheed, N. M., 1 May 2017, In : Journal of Biochemical and Molecular Toxicology. 31, 5, e21883.

Research output: Contribution to journalArticleResearchpeer-review

Sodium Nitrite
Quercetin
Rats
Apoptosis
Inflammation

Role of Different Natural Antioxidants in the Modulation of mRNA-expression of Apoptotic Molecules in the Livers of Carbon Tetrachloride-Intoxicated Rats

Al-Rasheed, N. M., El-Orabi, N. F., Fadda, L. M., Ali, H. M., Al-Rasheed, N. M., Bassiouni, Y. & Aldbass, A. M., 2 Oct 2017, In : Animal Biotechnology. 28, 4, p. 253-259 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Silymarin
silymarin
carbon tetrachloride
Carbon tetrachloride
Carbon Tetrachloride
16 Citations (Scopus)

Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats

Al-Rasheed, N. M., Al-Rasheed, N. M., Hasan, I. H., Al-Amin, M. A., Al-Ajmi, H. N., Mohamad, R. A. & Mahmoud, A. M., 1 Jan 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 1092015.

Research output: Contribution to journalArticleResearchpeer-review

Diabetic Cardiomyopathies
Oxidative stress
Simvastatin
Rats
Oxidative Stress
7 Citations (Scopus)

Thiolated alginate-based multiple layer mucoadhesive films of metformin forintra-pocket local delivery: in vitro characterization and clinical assessment

Kassem, A. A., Issa, D. A. E., Kotry, G. S. & Farid, R. M., 2 Jan 2017, In : Drug Development and Industrial Pharmacy. 43, 1, p. 120-131 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Metformin
Methylcellulose
Pharmaceutical Preparations
Sodium
Periodontal Pocket
2016

Amelioration of insulin, leptin and adiponectin levels in experimental metabolic syndrome model by some drugs

Al-Rasheed, N. M., Abdelkarem, H. M., Fadda, L. M., Mohamed, A. M., Al-Rasheed, N. M., Bassiouni, Y., Ali, H. M. & Gafeer, A. H., 1 Jan 2016, In : Indian Journal of Pharmaceutical Sciences. 78, 6, p. 701-707 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Adiponectin
Leptin
Insulin
Pharmaceutical Preparations
Hyperlipidemias
12 Citations (Scopus)

Disease specific modeling: Simulation of the pharmacokinetics of meloxicam and ibuprofen in disease state vs. healthy conditions

Almukainzi, M., Jamali, F., Aghazadeh-Habashi, A. & Löbenberg, R., 1 Mar 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 77-84 8 p.

Research output: Contribution to journalArticleResearchpeer-review

meloxicam
Ibuprofen
Stomach
Pharmacokinetics
Control Groups
2 Citations (Scopus)

Down-regulation of NFkB, Bax,TGF-β, Smad-2mRNA expression in the livers of carbon tetrachloride treated rats using different natural antioxidants

Al-Rasheed, N. M., Fadda, L. M., Al-Rasheed, N. M., Ali, H. M. & Yacoub, H. I., 1 Jan 2016, In : Brazilian Archives of Biology and Technology. 59, e16150553.

Research output: Contribution to journalArticleResearchpeer-review

Silymarin
Carbon Tetrachloride
Chlorogenic Acid
Melatonin
Down-Regulation

Erratum: Role of quercetin and arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats [BMC Complement Altern Med. 12, (2012) (60)], DOI: 10.1186/s12906-016-1291-x

Faddah, L. M., Abdel Baky, N. A., Al-Rasheed, N. M., Al-Rasheed, N. M., Fatani, A. J. & Atteya, M., 26 Aug 2016, In : BMC Complementary and Alternative Medicine. 16, 1, 323.

Research output: Contribution to journalComment/debateResearchpeer-review

Zinc Oxide
Quercetin
Arginine
Publications
8 Citations (Scopus)

Fenofibrate attenuates diabetic nephropathy in experimental diabetic rat's model via suppression of augmented TGF-β1/Smad3 signaling pathway

Al-Rasheed, N. M., Al-Rasheed, N. M., Al-Amin, M. A., Hasan, I. H., Al-Ajmi, H. N., Mohammad, R. A. & Attia, H. A., 7 Aug 2016, In : Archives of Physiology and Biochemistry. 122, 4, p. 186-194 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Fenofibrate
Diabetic Nephropathies
Transforming Growth Factors
Streptozocin
Kidney
6 Citations (Scopus)

Formulation approaches of triptans for management of migraine

Kassem, A. A., 1 Sep 2016, In : Current Drug Delivery. 13, 6, p. 882-898 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Tryptamines
Migraine Disorders
Biological Availability
Sumatriptan
zolmitriptan

Modulation of glutathione, phospholipids and lipid peroxides liver contents induced by zinc oxide nanoparticles using natural antioxidants

Al-Rasheed, N. M., Fadda, L. M., Ali, H. M. & Abdel Baky, N. A., 1 Jan 2016, In : Digest Journal of Nanomaterials and Biostructures. 11, 1, p. 303-312 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Zinc Oxide
glutathione
Lipid Peroxides
Phospholipids
antioxidants
8 Citations (Scopus)

Neuroprotective effect of carnosine and cyclosporine-A against inflammation, apoptosis, and oxidative brain damage after closed head injury in immature rats

Baky, N. A. A., Fadda, L., Al-Rasheed, N. M., Al-Rasheed, N. M., Mohamed, A. & Yacoub, H., 2 Jan 2016, In : Toxicology Mechanisms and Methods. 26, 1, p. 1-10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Carnosine
Closed Head Injuries
Neuroprotective Agents
Cyclosporine
Rats
6 Citations (Scopus)

New mechanism in the modulation of carbon tetrachloride hepatotoxicity in rats using different natural antioxidants

Al-Rasheed, N. M., Fadda, L. M., Ali, H. M., Abdel Baky, N. A., El-Orabi, N. F., Al-Rasheed, N. M. & Yacoub, H. I., 23 Mar 2016, In : Toxicology Mechanisms and Methods. 26, 4, p. 243-250 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Silymarin
Carbon Tetrachloride
Curcumin
Rats
Vitamin E
4 Citations (Scopus)

Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects

Al-Samhari, M. M., Al-Rasheed, N. M., Al-Rejaie, S., Al-Rasheed, N. M., Hasan, I. H., Mahmoud, A. M. & Dzimiri, N., 1 Mar 2016, In : Experimental Biology and Medicine. 241, 5, p. 509-518 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Acetylcysteine
Antidepressive Agents
Fluoxetine
Glutathione
Rats

Promising method in formulating ocular bio-adhesive inserts of ciprofloxacin hydrochloride combination with xanthan gum and carbopol

Al-Shawwa, S. Z., Obaidat, A. A., Sallam, A. A. & Salem, M. S., 1 Jan 2016, In : Latin American Journal of Pharmacy. 35, 7, p. 1607-1617 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Ciprofloxacin
Adhesives
Propylene Glycol
Drug Delivery Systems
Pharmacopoeias
2 Citations (Scopus)

Regulating effect of carnosine and/or L-arginine on the expression of inflammatory molecules induced nephropathy in the hypoxic rat model

Al-Rasheed, N. M., Fadda, L., Mohamed, A. M., Attia, H. A. & Al-Rasheed, N. M., 1 Jan 2016, In : Brazilian Archives of Biology and Technology. 59, e16150622.

Research output: Contribution to journalArticleResearchpeer-review

Carnosine
Arginine
Kidney
Body Weight
Lymphotoxin-beta
8 Citations (Scopus)

Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways

Al-Onazi, A. S., Al-Rasheed, N. M., Attia, H. A., Al-Rasheed, N. M., Ahmed, R. M., Al-Amin, M. A. & Poizat, C., 1 Feb 2016, In : Journal of Pharmacy and Pharmacology. 68, 2, p. 219-232 14 p.

Research output: Contribution to journalArticleResearchpeer-review

ruboxistaurin
Diabetic Nephropathies
Valsartan
Smad3 Protein
Kidney
27 Citations (Scopus)

Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats

Al-Rasheed, N. M., Al-Rasheed, N. M., Hasan, I. H., Al-Amin, M. A., Al-Ajmi, H. N. & Mahmoud, A. M., 28 Jun 2016, In : Drug Design, Development and Therapy. 10, p. 2095-2107 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Janus Kinases
Transducers
Cardiomyopathies
Hyperlipidemias
Diabetic Cardiomyopathies
6 Citations (Scopus)
Tissue Inhibitor of Metalloproteinases
NF-kappa B
Liver
Tissue Inhibitor of Metalloproteinase-2
Tissue Inhibitor of Metalloproteinase-1
2015
23 Citations (Scopus)
Hepatic Stellate Cells
Carbon Tetrachloride
Coffee
Transforming Growth Factors
Liver Cirrhosis
6 Citations (Scopus)

Assessment of the potential role of silymarin alone or in combination with vitamin E and/or curcumin on the carbon tetrachloride induced liver injury in rat

Al-Rasheed, N., Faddah, L., Sharaf, I. A., Mohamed, A. M., Al-Rasheed, N. & Abdelbaky, N., 1 Jan 2015, In : Brazilian Archives of Biology and Technology. 58, 6, p. 833-842 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Silymarin
Curcumin
Carbon Tetrachloride
Vitamin E
Liver
1 Citation (Scopus)

Determination of cefdinir in human plasma using HPLC coupled with tandem mass spectroscopy: Application to bioequivalence studies

Tutunji, L. F., Al Bayyari, M., Shilbayeh, S. & Tutunji, M. F., 1 Jan 2015, In : Jordan Journal of Pharmaceutical Sciences. 8, 2, p. 123-139 17 p.

Research output: Contribution to journalArticleResearchpeer-review

cefdinir
Therapeutic Equivalency
Mass Spectrometry
High Pressure Liquid Chromatography
Cephalexin
14 Citations (Scopus)

Development of gastroretentive metronidazole floating raft system for targeting Helicobacter pylori

Abou Youssef, N. A. H., Kassem, A. A., El-Massik, M. A. E. & Boraie, N. A., 30 May 2015, In : International Journal of Pharmaceutics. 486, 1-2, p. 297-305 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Stearates
Metronidazole
Helicobacter pylori
Lipids
Stomach
11 Citations (Scopus)

Development of mucoadhesive microbeads using thiolated sodium alginate for intrapocket delivery of resveratrol

Kassem, A. A., Farid, R. M., Issa, D. A. E., Khalil, D. S., Abd-El-Razzak, M. Y., Saudi, H. I., Eltokhey, H. M. & El-Zamarany, E. A., 20 Jun 2015, In : International Journal of Pharmaceutics. 487, 1-2, p. 305-313 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Microspheres
Electrons
Periodontal Pocket
resveratrol
alginic acid
8 Citations (Scopus)

Impaired ILK function is associated with deficits in hippocampal based memory and synaptic plasticity in a FASD rat model

Bhattacharya, D., Dunaway, E. P., Bhattacharya, S., Bloemer, J., Buabeid, M., Escobar, M., Suppiramaniam, V. & Dhanasekaran, M., 25 Aug 2015, In : PLoS ONE. 10, 8, e0135700.

Research output: Contribution to journalArticleResearchpeer-review

fetal alcohol syndrome
Fetal Alcohol Spectrum Disorders
Neuronal Plasticity
integrins
Plasticity
9 Citations (Scopus)

Preparation and evaluation of periodontal films based on polyelectrolyte complex formation

Kassem, A. A., Ismail, F. A., Naggar, V. F. & Aboulmagd, E., 1 May 2015, In : Pharmaceutical Development and Technology. 20, 3, p. 297-305 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Periodontal Pocket
Equipment and Supplies
Differential Scanning Calorimetry
Anti-Infective Agents
Tetracycline
2 Citations (Scopus)

Quantitation of the impact of CYP3A5 A6986G polymorphism on quetiapine pharmacokinetics by simulation of target attainment

Shilbayeh, S. A. R., Sy, S. K. B., Melhem, M., Zmeili, R. & Derendorf, H., 1 Jan 2015, In : Clinical Pharmacology in Drug Development. 4, 5, p. 387-394 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cytochrome P-450 CYP3A
Pharmacokinetics
Genotype
Clinical Pharmacology
Drug Monitoring
6 Citations (Scopus)

Renoprotective effects of fenofibrate via modulation of LKB1/AMPK mRNA expression and endothelial dysfunction in a rat model of diabetic nephropathy

Al-Rasheed, N. M., Al-Rasheed, N. M., Attia, H. A., Al-Amin, M. A., Al-Ajmi, H. N., Hasan, I. H., Mohamad, R. A. & Sinjilawi, N. A., 1 Dec 2015, In : Pharmacology. 95, 5-6, p. 229-239 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Fenofibrate
Diabetic Nephropathies
Adenosine Monophosphate
Protein Kinases
Phosphotransferases
1 Citation (Scopus)

Role of carnosine and melatonin in ameliorating cardiotoxicity of titanium dioxide nanoparticles in the rats

Al-Rasheed, N., Faddah, L., Ibrahim, H., Mohamed, A. M., Al-Rasheed, N. & Abdelbaky, N., 1 Jan 2015, In : Brazilian Archives of Biology and Technology. 58, 4, p. 577-586 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Carnosine
Melatonin
Nanoparticles
Biomarkers
Troponin T

Role of natural antioxidants in the modulation of plasma amino acid pattern in rats exposed to hemic hypoxia

Al-Rasheed, N. M., Fadda, L. M., Al-Rasheed, N. M., Attia, H., Ali, H. M. & El-Agami, H., 1 Jan 2015, In : Brazilian Archives of Biology and Technology. 58, 5, p. 741-749 9 p.

Research output: Contribution to journalArticleResearchpeer-review

carnosine
hypoxia
sodium nitrite
antioxidants
amino acids
18 Citations (Scopus)

Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway

Al-Rasheed, N. M., Al-Oteibi, M. M., Al-Manee, R. Z., Al-Shareef, S. A., Al-Rasheed, N. M., Hasan, I. H., Mohamad, R. A. & Mahmoud, A. M., 23 Jun 2015, In : Drug Design, Development and Therapy. 9, p. 3217-3229 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Simvastatin
Cardiomegaly
Isoproterenol
Janus Kinases
Transducers
3 Citations (Scopus)

The combination of zinc and glibenclamide limits cardiovascular complications in diabetic rats via multiple mechanisms

Attia, H., Al-Rasheed, N., Al-Rasheed, N. & Faddah, L., 1 Jan 2015, In : Pakistan Journal of Pharmaceutical Sciences. 28, 2, p. 499-508 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Glyburide
Diabetes Complications
Zinc
Vascular Endothelial Growth Factor A
Nitric Oxide
18 Citations (Scopus)

Vitamin D attenuates pro-inflammatory TNF-α cytokine expression by inhibiting NF-кB/p65 signaling in hypertrophied rat hearts

Al-Rasheed, N. M., Al-Rasheed, N. M., Bassiouni, Y. A., Hasan, I. H., Al-Amin, M. A., Al-Ajmi, H. N. & Mohamad, R. A., 1 Jun 2015, In : Journal of Physiology and Biochemistry. 71, 2, p. 289-299 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Vitamin D
Rats
Cardiomegaly
Tumor Necrosis Factor-alpha
Cytokines
2014
3 Citations (Scopus)

Biorelevant Dissolution Testing

Almukainzi, M., Bou-Chacra, N. A., Walker, R. B. & Lo¨benberg, R., 28 Jul 2014, Therapeutic Delivery Solutions. Wiley-Blackwell, p. 335-365 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Dissolution
Testing
Product development
Quality control
Specifications