Antibacterial, Antioxidant Activity of Ethanolic Plant Extracts of Some Convolvulus Species and Their DART-ToF-MS Profiling

Asma'A Al-Rifai, Ahmad Aqel, Tarfah Al-Warhi, Saikh M. Wabaidur, Zeid A. Al-Othman, A. Yacine Badjah-Hadj-Ahmed

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

Convolvulus austroaegyptiacus Abdallah & Sa'ad (CA) and Convolvulus pilosellifolius Desr. (CP) are commonly used in the Saudi Arabia folk medicine. They are potent in treating the ulcers and skin diseases. The lack of information about their biological activities led us to investigate the possible biological activities by determination of antibacterial and antioxidant activities of total ethanolic extracts and various fractions. Total flavonoid contents of the plants were determined by colorimetric method while total phenols were determined by using Folin-Ciocalteu method. In vitro antibacterial activity was studied against E. coli, P. aeruginosa, and B. subtilis, and the total antioxidant capacity was evaluated by radical scavenging method. IC50 were found to be 21.81, 17.62, and 3.31 μg/mL for CA, CP, and vitamin C, respectively, while the lowest MIC value of 0.25 mg/mL was recorded with CP extract against B. subtilis. Around 21 compounds are tentatively elucidated from both plants using rapid, simple, and high-resolution analytical technique for chemical profiling of natural compounds by direct analysis in real-time of flight-mass spectrometry, of which 17 were not isolated or reported previously.

Original languageEnglish
Article number5694305
JournalEvidence-based Complementary and Alternative Medicine
Volume2017
DOIs
Publication statusPublished - 1 Jan 2017

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Convolvulus
Plant Extracts
Antioxidants
Saudi Arabia
Phenols
Traditional Medicine
Skin Diseases
Flavonoids
Ascorbic Acid
Inhibitory Concentration 50
Ulcer
Mass Spectrometry
Escherichia coli

Cite this

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title = "Antibacterial, Antioxidant Activity of Ethanolic Plant Extracts of Some Convolvulus Species and Their DART-ToF-MS Profiling",
abstract = "Convolvulus austroaegyptiacus Abdallah & Sa'ad (CA) and Convolvulus pilosellifolius Desr. (CP) are commonly used in the Saudi Arabia folk medicine. They are potent in treating the ulcers and skin diseases. The lack of information about their biological activities led us to investigate the possible biological activities by determination of antibacterial and antioxidant activities of total ethanolic extracts and various fractions. Total flavonoid contents of the plants were determined by colorimetric method while total phenols were determined by using Folin-Ciocalteu method. In vitro antibacterial activity was studied against E. coli, P. aeruginosa, and B. subtilis, and the total antioxidant capacity was evaluated by radical scavenging method. IC50 were found to be 21.81, 17.62, and 3.31 μg/mL for CA, CP, and vitamin C, respectively, while the lowest MIC value of 0.25 mg/mL was recorded with CP extract against B. subtilis. Around 21 compounds are tentatively elucidated from both plants using rapid, simple, and high-resolution analytical technique for chemical profiling of natural compounds by direct analysis in real-time of flight-mass spectrometry, of which 17 were not isolated or reported previously.",
author = "Asma'A Al-Rifai and Ahmad Aqel and Tarfah Al-Warhi and Wabaidur, {Saikh M.} and Al-Othman, {Zeid A.} and Badjah-Hadj-Ahmed, {A. Yacine}",
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Antibacterial, Antioxidant Activity of Ethanolic Plant Extracts of Some Convolvulus Species and Their DART-ToF-MS Profiling. / Al-Rifai, Asma'A; Aqel, Ahmad; Al-Warhi, Tarfah; Wabaidur, Saikh M.; Al-Othman, Zeid A.; Badjah-Hadj-Ahmed, A. Yacine.

In: Evidence-based Complementary and Alternative Medicine, Vol. 2017, 5694305, 01.01.2017.

Research output: Contribution to journalArticleResearchpeer-review

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