Complex formation reactions of palladium(II) and amlodipine drug with biologically active ligands

Salhah D. Al-Qahtani, Reda A. Ammar, Lamina A. Al-Bedair, Azaa F. Alshalawi

Research output: Contribution to journalArticle

Abstract

The stability constants of various complexes of [Pd(drug)(H2O)2]2+ (drug = amlodipine) with peptides, (L) viz. glycylglycine, leucylalanine, glycylvaline, glycinamide and glutamine have been studied using potentiometric measurements. The complexes formation procedure has been predictable according to the pH range studied. A different complexes constants were determined under 0.1 mol/dm3 NaNO3 and 25 °C conditions such as stability and stoichiometries constants.

Original languageEnglish
Pages (from-to)1669-1672
Number of pages4
JournalAsian Journal of Chemistry
Volume29
Issue number8
DOIs
Publication statusPublished - 1 Jan 2017

Fingerprint

Amlodipine
Palladium
glycylvaline
leucyl-alanine
Glycylglycine
Ligands
Glutamine
Stoichiometry
Pharmaceutical Preparations
glycine amide
peptide L

Keywords

  • Drug
  • Peptides
  • Potentiometric studies
  • Solution equilibria
  • Stability constants

Cite this

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title = "Complex formation reactions of palladium(II) and amlodipine drug with biologically active ligands",
abstract = "The stability constants of various complexes of [Pd(drug)(H2O)2]2+ (drug = amlodipine) with peptides, (L) viz. glycylglycine, leucylalanine, glycylvaline, glycinamide and glutamine have been studied using potentiometric measurements. The complexes formation procedure has been predictable according to the pH range studied. A different complexes constants were determined under 0.1 mol/dm3 NaNO3 and 25 °C conditions such as stability and stoichiometries constants.",
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Complex formation reactions of palladium(II) and amlodipine drug with biologically active ligands. / Al-Qahtani, Salhah D.; Ammar, Reda A.; Al-Bedair, Lamina A.; Alshalawi, Azaa F.

In: Asian Journal of Chemistry, Vol. 29, No. 8, 01.01.2017, p. 1669-1672.

Research output: Contribution to journalArticle

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AU - Ammar, Reda A.

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