Myofibroblastoma of the mandible in a 3-year-old child

Saad Hajeri, Abdulsalam Al Jabab, Manal Al Sheddi, Hanadi Fatani

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Myofibroblastoma is a rare benign tumor of the head and neck region, which is characterized by a large, rapidly growing, and destructive mass. A 3-year-old boy presented with an 8-week history of a rapidly growing swelling of the right mandible. Examination revealed a firm 13-cm mass occupying the entire right body and ramus of the mandible. The clinical and radiological features were suggestive of a sarcoma. An initial biopsy taken in the referring hospital was inconclusive, and the second biopsy showed a myofibroblastic neoplasm consistent with a desmoplastic fibroma. Progressive tumor growth necessitated a tracheostomy. Right hemimandibulectomy was performed, and the defect was reconstructed with free microvascular fibula flap. Histopathology and immunocytochemistry revealed a myofibroblastoma. This entity differs from other myofibroblasts and fibroblast tumors such as inflammatory myofibroblastic tumor (IMT), myofibroma, and desmoplastic fibroma. The child has been followed up for 2 years. Conclusion: Differentiation between myofibroblasts and fibroblastic tumors as well as some malignancies can be challenging. Myofibroblastoma can behave as a malignant neoplasm, and the clinical distinction of this entity lies primarily in its recognition as a benign neoplasm.

Original languageEnglish
Pages (from-to)103-107
Number of pages5
JournalOral and Maxillofacial Surgery
Volume20
Issue number1
DOIs
Publication statusPublished - 1 Mar 2016

Fingerprint

Muscle Tissue Neoplasms
Mandible
Neoplasms
Desmoplastic Fibroma
Myofibroblasts
Myofibroma
Mandibular Osteotomy
Biopsy
Fibula
Tracheostomy
Sarcoma
Neck
Fibroblasts
Immunohistochemistry
Head

Keywords

  • Myofibroblastoma

Cite this

Hajeri, Saad ; Al Jabab, Abdulsalam ; Al Sheddi, Manal ; Fatani, Hanadi. / Myofibroblastoma of the mandible in a 3-year-old child. In: Oral and Maxillofacial Surgery. 2016 ; Vol. 20, No. 1. pp. 103-107.
@article{c48c2113fca84ffb9724f3f5a8883b76,
title = "Myofibroblastoma of the mandible in a 3-year-old child",
abstract = "Myofibroblastoma is a rare benign tumor of the head and neck region, which is characterized by a large, rapidly growing, and destructive mass. A 3-year-old boy presented with an 8-week history of a rapidly growing swelling of the right mandible. Examination revealed a firm 13-cm mass occupying the entire right body and ramus of the mandible. The clinical and radiological features were suggestive of a sarcoma. An initial biopsy taken in the referring hospital was inconclusive, and the second biopsy showed a myofibroblastic neoplasm consistent with a desmoplastic fibroma. Progressive tumor growth necessitated a tracheostomy. Right hemimandibulectomy was performed, and the defect was reconstructed with free microvascular fibula flap. Histopathology and immunocytochemistry revealed a myofibroblastoma. This entity differs from other myofibroblasts and fibroblast tumors such as inflammatory myofibroblastic tumor (IMT), myofibroma, and desmoplastic fibroma. The child has been followed up for 2 years. Conclusion: Differentiation between myofibroblasts and fibroblastic tumors as well as some malignancies can be challenging. Myofibroblastoma can behave as a malignant neoplasm, and the clinical distinction of this entity lies primarily in its recognition as a benign neoplasm.",
keywords = "Myofibroblastoma",
author = "Saad Hajeri and {Al Jabab}, Abdulsalam and {Al Sheddi}, Manal and Hanadi Fatani",
year = "2016",
month = "3",
day = "1",
doi = "10.1007/s10006-015-0524-3",
language = "English",
volume = "20",
pages = "103--107",
journal = "Oral and Maxillofacial Surgery",
issn = "1865-1550",
publisher = "Springer Verlag",
number = "1",

}

Myofibroblastoma of the mandible in a 3-year-old child. / Hajeri, Saad; Al Jabab, Abdulsalam; Al Sheddi, Manal; Fatani, Hanadi.

In: Oral and Maxillofacial Surgery, Vol. 20, No. 1, 01.03.2016, p. 103-107.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Myofibroblastoma of the mandible in a 3-year-old child

AU - Hajeri, Saad

AU - Al Jabab, Abdulsalam

AU - Al Sheddi, Manal

AU - Fatani, Hanadi

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Myofibroblastoma is a rare benign tumor of the head and neck region, which is characterized by a large, rapidly growing, and destructive mass. A 3-year-old boy presented with an 8-week history of a rapidly growing swelling of the right mandible. Examination revealed a firm 13-cm mass occupying the entire right body and ramus of the mandible. The clinical and radiological features were suggestive of a sarcoma. An initial biopsy taken in the referring hospital was inconclusive, and the second biopsy showed a myofibroblastic neoplasm consistent with a desmoplastic fibroma. Progressive tumor growth necessitated a tracheostomy. Right hemimandibulectomy was performed, and the defect was reconstructed with free microvascular fibula flap. Histopathology and immunocytochemistry revealed a myofibroblastoma. This entity differs from other myofibroblasts and fibroblast tumors such as inflammatory myofibroblastic tumor (IMT), myofibroma, and desmoplastic fibroma. The child has been followed up for 2 years. Conclusion: Differentiation between myofibroblasts and fibroblastic tumors as well as some malignancies can be challenging. Myofibroblastoma can behave as a malignant neoplasm, and the clinical distinction of this entity lies primarily in its recognition as a benign neoplasm.

AB - Myofibroblastoma is a rare benign tumor of the head and neck region, which is characterized by a large, rapidly growing, and destructive mass. A 3-year-old boy presented with an 8-week history of a rapidly growing swelling of the right mandible. Examination revealed a firm 13-cm mass occupying the entire right body and ramus of the mandible. The clinical and radiological features were suggestive of a sarcoma. An initial biopsy taken in the referring hospital was inconclusive, and the second biopsy showed a myofibroblastic neoplasm consistent with a desmoplastic fibroma. Progressive tumor growth necessitated a tracheostomy. Right hemimandibulectomy was performed, and the defect was reconstructed with free microvascular fibula flap. Histopathology and immunocytochemistry revealed a myofibroblastoma. This entity differs from other myofibroblasts and fibroblast tumors such as inflammatory myofibroblastic tumor (IMT), myofibroma, and desmoplastic fibroma. The child has been followed up for 2 years. Conclusion: Differentiation between myofibroblasts and fibroblastic tumors as well as some malignancies can be challenging. Myofibroblastoma can behave as a malignant neoplasm, and the clinical distinction of this entity lies primarily in its recognition as a benign neoplasm.

KW - Myofibroblastoma

UR - http://www.scopus.com/inward/record.url?scp=84958878590&partnerID=8YFLogxK

U2 - 10.1007/s10006-015-0524-3

DO - 10.1007/s10006-015-0524-3

M3 - Article

VL - 20

SP - 103

EP - 107

JO - Oral and Maxillofacial Surgery

JF - Oral and Maxillofacial Surgery

SN - 1865-1550

IS - 1

ER -