Pulmonary arterial hypertension in Saudi Arabia

Patients′ clinical and physiological characteristics and hemodynamic parameters. A single center experience

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Aims: The main objective of this study is to describe patients′ clinical characteristics and physiological and hemodynamic parameters at the time of diagnosis in a pulmonary hypertension center in Saudi Arabia.

Materials and Methods: This study reports the results from a single pulmonary hypertension specialized center in Riyadh, Saudi Arabia, namely Prince Sultan Medical Military City/Cardiac Center (PSMMC & CC). Both newly diagnosed (incidence) and referred (prevalence) cases of pulmonary arterial hypertension are included. All characteristics, including clinical, physiological, and hemodynamic parameters at the time of diagnosis are described.

Results: A total of 107 patients were identified as having pulmonary arterial hypertension as diagnosed by right heart catheterization. The mean age at diagnosis was 36 (± 9) years, and there was a female preponderance of 62.6%. The mean duration between symptom onset and diagnosis was 27.8 (± 9.0) months. At the time of enrollment, 56.1% of patients were in functional class III and 16.8% were in functional class IV. Fifty five patients (51.4%) were diagnosed as idiopathic pulmonary arterial hypertension, 29 patients (27.1%) as congenital heart disease associated with pulmonary arterial hypertension, 16 patients (15.0%) as connective tissue diseases associated with pulmonary arterial hypertension, 4 patients (3.7%) as heritable pulmonary arterial hypertension, and 3 patients (2.8%) as portopulmonary hypertension.

Conclusion: This data highlights the current situation of pulmonary arterial hypertension in Saudi Arabia. Our patients are much younger than patients described in other international registries but still detected as late in the course of the disease. A majority of patients displays severe functional and hemodynamic compromise.

Original languageEnglish
Pages (from-to)209-215
Number of pages7
JournalAnnals of Thoracic Medicine
Volume9
Issue number4
DOIs
Publication statusPublished - 1 Jan 2014

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Saudi Arabia
Pulmonary Hypertension
Hemodynamics
Connective Tissue Diseases
Cardiac Catheterization
Registries
Heart Diseases
Hypertension

Keywords

  • Hemodynamics
  • pulmonary arterial hypertension
  • registry
  • Saudi Arabia
  • Saudi association for pulmonary hypertension
  • six minute walk test

Cite this

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title = "Pulmonary arterial hypertension in Saudi Arabia: Patients′ clinical and physiological characteristics and hemodynamic parameters. A single center experience",
abstract = "Aims: The main objective of this study is to describe patients′ clinical characteristics and physiological and hemodynamic parameters at the time of diagnosis in a pulmonary hypertension center in Saudi Arabia.Materials and Methods: This study reports the results from a single pulmonary hypertension specialized center in Riyadh, Saudi Arabia, namely Prince Sultan Medical Military City/Cardiac Center (PSMMC & CC). Both newly diagnosed (incidence) and referred (prevalence) cases of pulmonary arterial hypertension are included. All characteristics, including clinical, physiological, and hemodynamic parameters at the time of diagnosis are described.Results: A total of 107 patients were identified as having pulmonary arterial hypertension as diagnosed by right heart catheterization. The mean age at diagnosis was 36 (± 9) years, and there was a female preponderance of 62.6{\%}. The mean duration between symptom onset and diagnosis was 27.8 (± 9.0) months. At the time of enrollment, 56.1{\%} of patients were in functional class III and 16.8{\%} were in functional class IV. Fifty five patients (51.4{\%}) were diagnosed as idiopathic pulmonary arterial hypertension, 29 patients (27.1{\%}) as congenital heart disease associated with pulmonary arterial hypertension, 16 patients (15.0{\%}) as connective tissue diseases associated with pulmonary arterial hypertension, 4 patients (3.7{\%}) as heritable pulmonary arterial hypertension, and 3 patients (2.8{\%}) as portopulmonary hypertension.Conclusion: This data highlights the current situation of pulmonary arterial hypertension in Saudi Arabia. Our patients are much younger than patients described in other international registries but still detected as late in the course of the disease. A majority of patients displays severe functional and hemodynamic compromise.",
keywords = "Hemodynamics, pulmonary arterial hypertension, registry, Saudi Arabia, Saudi association for pulmonary hypertension, six minute walk test",
author = "Idrees, {M. M.} and K. Al-Najashi and A. Khan and S. Al-Dammas and H. Al-Awwad and E. Batubara and {Al Otai}, A. and J. Abdulhameed and A. Fayed and T. Kashour",
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Pulmonary arterial hypertension in Saudi Arabia : Patients′ clinical and physiological characteristics and hemodynamic parameters. A single center experience. /.

In: Annals of Thoracic Medicine, Vol. 9, No. 4, 01.01.2014, p. 209-215.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Pulmonary arterial hypertension in Saudi Arabia

T2 - Patients′ clinical and physiological characteristics and hemodynamic parameters. A single center experience

AU - Idrees, M. M.

AU - Al-Najashi, K.

AU - Khan, A.

AU - Al-Dammas, S.

AU - Al-Awwad, H.

AU - Batubara, E.

AU - Al Otai, A.

AU - Abdulhameed, J.

AU - Fayed, A.

AU - Kashour, T.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Aims: The main objective of this study is to describe patients′ clinical characteristics and physiological and hemodynamic parameters at the time of diagnosis in a pulmonary hypertension center in Saudi Arabia.Materials and Methods: This study reports the results from a single pulmonary hypertension specialized center in Riyadh, Saudi Arabia, namely Prince Sultan Medical Military City/Cardiac Center (PSMMC & CC). Both newly diagnosed (incidence) and referred (prevalence) cases of pulmonary arterial hypertension are included. All characteristics, including clinical, physiological, and hemodynamic parameters at the time of diagnosis are described.Results: A total of 107 patients were identified as having pulmonary arterial hypertension as diagnosed by right heart catheterization. The mean age at diagnosis was 36 (± 9) years, and there was a female preponderance of 62.6%. The mean duration between symptom onset and diagnosis was 27.8 (± 9.0) months. At the time of enrollment, 56.1% of patients were in functional class III and 16.8% were in functional class IV. Fifty five patients (51.4%) were diagnosed as idiopathic pulmonary arterial hypertension, 29 patients (27.1%) as congenital heart disease associated with pulmonary arterial hypertension, 16 patients (15.0%) as connective tissue diseases associated with pulmonary arterial hypertension, 4 patients (3.7%) as heritable pulmonary arterial hypertension, and 3 patients (2.8%) as portopulmonary hypertension.Conclusion: This data highlights the current situation of pulmonary arterial hypertension in Saudi Arabia. Our patients are much younger than patients described in other international registries but still detected as late in the course of the disease. A majority of patients displays severe functional and hemodynamic compromise.

AB - Aims: The main objective of this study is to describe patients′ clinical characteristics and physiological and hemodynamic parameters at the time of diagnosis in a pulmonary hypertension center in Saudi Arabia.Materials and Methods: This study reports the results from a single pulmonary hypertension specialized center in Riyadh, Saudi Arabia, namely Prince Sultan Medical Military City/Cardiac Center (PSMMC & CC). Both newly diagnosed (incidence) and referred (prevalence) cases of pulmonary arterial hypertension are included. All characteristics, including clinical, physiological, and hemodynamic parameters at the time of diagnosis are described.Results: A total of 107 patients were identified as having pulmonary arterial hypertension as diagnosed by right heart catheterization. The mean age at diagnosis was 36 (± 9) years, and there was a female preponderance of 62.6%. The mean duration between symptom onset and diagnosis was 27.8 (± 9.0) months. At the time of enrollment, 56.1% of patients were in functional class III and 16.8% were in functional class IV. Fifty five patients (51.4%) were diagnosed as idiopathic pulmonary arterial hypertension, 29 patients (27.1%) as congenital heart disease associated with pulmonary arterial hypertension, 16 patients (15.0%) as connective tissue diseases associated with pulmonary arterial hypertension, 4 patients (3.7%) as heritable pulmonary arterial hypertension, and 3 patients (2.8%) as portopulmonary hypertension.Conclusion: This data highlights the current situation of pulmonary arterial hypertension in Saudi Arabia. Our patients are much younger than patients described in other international registries but still detected as late in the course of the disease. A majority of patients displays severe functional and hemodynamic compromise.

KW - Hemodynamics

KW - pulmonary arterial hypertension

KW - registry

KW - Saudi Arabia

KW - Saudi association for pulmonary hypertension

KW - six minute walk test

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U2 - 10.4103/1817-1737.140127

DO - 10.4103/1817-1737.140127

M3 - Article

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EP - 215

JO - Annals of Thoracic Medicine

JF - Annals of Thoracic Medicine

SN - 1817-1737

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