Spectroscopic, Molar Conductance and Biocidal Studies of Pt(IV), Au(III) and Pd(II) Chelates of Nitrogen and Oxygen Containing Schiff Base Derived from 4-Amino Antipyrine and 2-Furaldehyde

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Abstract

Pt(IV), Au(III) and Pd(II) complexes of Schiff bases derived from 2-furaldehyde and 4-amino antipyrine (4APF) are reported and characterized based on elemental analyses, IR 1H-NMR, electronic spectra, molar conductance, and thermal analysis (TG/DTG). The complexes are found to have the formulas [Pt(4APF)Cl]Cl3, [Pd(4APF)]Cl2 and [Au(4APF)(Cl)2]Cl. The molar conductance data reveal that all the metal chelates of the 4APF ligand are electrolytes with different numbers of ionizable chloride ions. IR spectra show that 4APF is coordinated to the metal ions in a bi-dentate situation, with ON donor sites of azomethine-N and furan-O, whereas the Pt(IV) metal ions is coordinated to the 4APF in a tri-dentate situation with ONO donor sites of azomethine-N, furan-O, and carbonyl-O. The thermal behavior of these chelates shows that the hydrated complexes lose water molecules of hydration in the first step and is followed by decomposition of the anions and ligand moieties in the respective steps. The synthesized ligands, in comparison to their metal complexes, were also screened for their antibacterial activity against bacterial species as well as fungi. The activity data show the metal complexes to be more potent antimicrobial than the parent Schiff base ligand.

Original languageEnglish
Pages (from-to)10424-10445
Number of pages22
JournalInternational Journal of Electrochemical Science
Volume8
Issue number8
Publication statusPublished - 2 Oct 2013

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Furaldehyde
Antipyrine
Schiff Bases
Nitrogen
Ligands
Oxygen
Coordination Complexes
Metal complexes
Metal ions
Fungi
Hydration
Thermoanalysis
Electrolytes
Anions
Chlorides
Negative ions
Metals
Nuclear magnetic resonance
Ions
Decomposition

Keywords

  • 1H-NMR
  • 2-furaldehyde
  • 4-Amino antipyrine
  • Biological and anticancer activities
  • IR
  • Noble metal
  • Thermal analysis

Cite this

@article{24275bbcae43457bb82f759afeeff1a2,
title = "Spectroscopic, Molar Conductance and Biocidal Studies of Pt(IV), Au(III) and Pd(II) Chelates of Nitrogen and Oxygen Containing Schiff Base Derived from 4-Amino Antipyrine and 2-Furaldehyde",
abstract = "Pt(IV), Au(III) and Pd(II) complexes of Schiff bases derived from 2-furaldehyde and 4-amino antipyrine (4APF) are reported and characterized based on elemental analyses, IR 1H-NMR, electronic spectra, molar conductance, and thermal analysis (TG/DTG). The complexes are found to have the formulas [Pt(4APF)Cl]Cl3, [Pd(4APF)]Cl2 and [Au(4APF)(Cl)2]Cl. The molar conductance data reveal that all the metal chelates of the 4APF ligand are electrolytes with different numbers of ionizable chloride ions. IR spectra show that 4APF is coordinated to the metal ions in a bi-dentate situation, with ON donor sites of azomethine-N and furan-O, whereas the Pt(IV) metal ions is coordinated to the 4APF in a tri-dentate situation with ONO donor sites of azomethine-N, furan-O, and carbonyl-O. The thermal behavior of these chelates shows that the hydrated complexes lose water molecules of hydration in the first step and is followed by decomposition of the anions and ligand moieties in the respective steps. The synthesized ligands, in comparison to their metal complexes, were also screened for their antibacterial activity against bacterial species as well as fungi. The activity data show the metal complexes to be more potent antimicrobial than the parent Schiff base ligand.",
keywords = "1H-NMR, 2-furaldehyde, 4-Amino antipyrine, Biological and anticancer activities, IR, Noble metal, Thermal analysis",
author = "Al-Saif, {Foziah A.}",
year = "2013",
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language = "English",
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T1 - Spectroscopic, Molar Conductance and Biocidal Studies of Pt(IV), Au(III) and Pd(II) Chelates of Nitrogen and Oxygen Containing Schiff Base Derived from 4-Amino Antipyrine and 2-Furaldehyde

AU - Al-Saif, Foziah A.

PY - 2013/10/2

Y1 - 2013/10/2

N2 - Pt(IV), Au(III) and Pd(II) complexes of Schiff bases derived from 2-furaldehyde and 4-amino antipyrine (4APF) are reported and characterized based on elemental analyses, IR 1H-NMR, electronic spectra, molar conductance, and thermal analysis (TG/DTG). The complexes are found to have the formulas [Pt(4APF)Cl]Cl3, [Pd(4APF)]Cl2 and [Au(4APF)(Cl)2]Cl. The molar conductance data reveal that all the metal chelates of the 4APF ligand are electrolytes with different numbers of ionizable chloride ions. IR spectra show that 4APF is coordinated to the metal ions in a bi-dentate situation, with ON donor sites of azomethine-N and furan-O, whereas the Pt(IV) metal ions is coordinated to the 4APF in a tri-dentate situation with ONO donor sites of azomethine-N, furan-O, and carbonyl-O. The thermal behavior of these chelates shows that the hydrated complexes lose water molecules of hydration in the first step and is followed by decomposition of the anions and ligand moieties in the respective steps. The synthesized ligands, in comparison to their metal complexes, were also screened for their antibacterial activity against bacterial species as well as fungi. The activity data show the metal complexes to be more potent antimicrobial than the parent Schiff base ligand.

AB - Pt(IV), Au(III) and Pd(II) complexes of Schiff bases derived from 2-furaldehyde and 4-amino antipyrine (4APF) are reported and characterized based on elemental analyses, IR 1H-NMR, electronic spectra, molar conductance, and thermal analysis (TG/DTG). The complexes are found to have the formulas [Pt(4APF)Cl]Cl3, [Pd(4APF)]Cl2 and [Au(4APF)(Cl)2]Cl. The molar conductance data reveal that all the metal chelates of the 4APF ligand are electrolytes with different numbers of ionizable chloride ions. IR spectra show that 4APF is coordinated to the metal ions in a bi-dentate situation, with ON donor sites of azomethine-N and furan-O, whereas the Pt(IV) metal ions is coordinated to the 4APF in a tri-dentate situation with ONO donor sites of azomethine-N, furan-O, and carbonyl-O. The thermal behavior of these chelates shows that the hydrated complexes lose water molecules of hydration in the first step and is followed by decomposition of the anions and ligand moieties in the respective steps. The synthesized ligands, in comparison to their metal complexes, were also screened for their antibacterial activity against bacterial species as well as fungi. The activity data show the metal complexes to be more potent antimicrobial than the parent Schiff base ligand.

KW - 1H-NMR

KW - 2-furaldehyde

KW - 4-Amino antipyrine

KW - Biological and anticancer activities

KW - IR

KW - Noble metal

KW - Thermal analysis

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