Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system

Fawad Javed, Shatha Subhi ALHarthi, Munerah Saleh BinShabaib, Sangeeta Gajendra, Georgios E. Romanos, Irfan Rahman

Research output: Contribution to journalReview articleResearchpeer-review

7 Citations (Scopus)

Abstract

Waterpipe smoking (WS), an emerging trend has major health concerns. It is prevalent worldwide as a recreational activity both indoors and outdoors. The aim of this review was to assess the impact of waterpipe smoke on the oral and respiratory system (oral cavity and pulmonary tissues). A number of studies have shown that periodontal health status is compromised in waterpipe smokers when compared with nonsmokers. Some studies have associated WS with oral premalignant and malignant lesions; however, due to the poor quality of these studies, the presented outcomes should be interpreted with caution. Although cigarette smoking has been considered as a potential risk factor for dental caries; there are no studies in indexed literature that have shown an association to exist between dental caries and WS. Inhaled waterpipe smoke imposes oxidative stress and inflammatory responses and compromises the ventilatory capacity of the lungs and may lead to an increased risk of decline in lung function. WS may cause oral and pulmonary diseases, such as periodontal disease and chronic obstructive airway disease, respectively. The association between WS and development of dental caries and oral pre-cancer and their relationships with chronic airways disease requires investigations. This review discusses the current evidence of waterpipe smoke effects on the oral health and respiratory system based on basic and clinical science and provides future directions for research and regulatory science on how WS can affect the oral cavity and the respiratory/pulmonary system.

Original languageEnglish
Pages (from-to)389-396
Number of pages8
JournalInhalation Toxicology
Volume29
Issue number9
DOIs
Publication statusPublished - 29 Jul 2017

Fingerprint

Respiratory system
Smoke
Respiratory System
Toxicology
Mouth
Smoking
Health
Association reactions
Dental Caries
Pulmonary diseases
Oxidative stress
Tobacco Products
Lung
Tissue
Mouth Diseases
Lung Volume Measurements
Mouth Neoplasms
Oral Health
Periodontal Diseases
Chronic Obstructive Pulmonary Disease

Keywords

  • cancer
  • COPD
  • Dental
  • hookah
  • narghile
  • oral
  • periodontal
  • pulmonary
  • smoking waterpipe

Cite this

Javed, Fawad ; ALHarthi, Shatha Subhi ; BinShabaib, Munerah Saleh ; Gajendra, Sangeeta ; Romanos, Georgios E. ; Rahman, Irfan. / Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system. In: Inhalation Toxicology. 2017 ; Vol. 29, No. 9. pp. 389-396.
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Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system. / Javed, Fawad; ALHarthi, Shatha Subhi; BinShabaib, Munerah Saleh; Gajendra, Sangeeta; Romanos, Georgios E.; Rahman, Irfan.

In: Inhalation Toxicology, Vol. 29, No. 9, 29.07.2017, p. 389-396.

Research output: Contribution to journalReview articleResearchpeer-review

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